Indications for the prescribing of “Loperamide”
“Loperamide” are prescribed in acute and chronic diarrhea of different origin (allergic, medicinal, emotional, radiation), in case of nutritional disorders and changes to the composition of the diet, in case of metabolic and absorption disorders, in the regulation of stool in patients having ileostoma as an aid in diarrhea caused by infections. After ingestion, “Loperamide” has a rapid effect that lasts 4-6 hours.
Instructions for use of “Loperamide”
Capsules “Loperamida” are filled with water, a lingual tablet is put on the tongue, which disintegrates after a few seconds, and it is swallowed with saliva. Lingual tablet is not necessary.
While taking “Loperamide”, a tingling or burning tongue may appear in the form of pickling tablets.
Adults with acute diarrhea “Loperamide” should be taken at the first dose of 4 mg, subsequently after each case of diarrhea of 2 mg. The maximum daily dose of 16 milligrams cannot be exceeded. Adults with chronic diarrhea are prescribed “Loperamide” in the first dose of 2 mg, selecting the maintenance dose so that the stool appears 1-2 times a day. The maintenance dose can be 2-12 mg per day.
Children aged 5 years with acute diarrhea are given the initial dose of the drug – 2 mg, then given 2 milligrams after each case of diarrhea, maximum daily dose of “Loperamide” for children is 8 mg. Children aged 5 years with chronic diarrhea loperamide are given 2 mg per daily dose. Children aged two to five years are prescribed a solution for oral use depending on the weight of the child – five milliliters per ten kilograms of body weight, 2-3 times a day. The highest daily dose is 6 mg per 20 kg of body weight.
The reception of “Loperamide” must be stopped as soon as there is a normal chair or the chair will be absent for more than 12 hours.
Side effects and contraindications to the use of “Loperamide”
“Loperamide” are contraindicated in hypersensitivity, acute ulcerative, $ colitis of intestinal obstruction, diverticulosis, diarrhea caused by pseudomembranous enterocolitis, dysentery and other GI infections. “Loperamide” is not prescribed in the first trimester of pregnancy, nor during breastfeeding; to children under two years of age. In case of liver failure it is applied with caution.
“ Loperamide” can cause the following adverse effects: allergic reactions to the skin (rash), dizziness, drowsiness, dry mouth, electrolyte disorders, intestinal colic, nausea, vomiting, flatulence, constipation, discomfort or abdominal pain. Occasionally, urinary retention and intestinal obstruction can appear. In overdose of “Loperamide”, the following manifestations are observed: oppression of the central nervous system (oppression of breathing, stupor, drowsiness, disorders of coordination of movements), intestinal obstruction. Symptomatic treatment: prescribed activated charcoal, antidote — naloxone, rinse the stomach.