Anapriline: Application Instruction

Description and characteristics of the drug

The main active substance of Anaprilin is propranolol hydrochloride, which is antianginal, hypotensive and anti-arrhythmic remedy. One tablet of Anapriline propranolol hydrochloride contains 10 mg or 40 mg. Excipients included in the drug: calcium stearate, colloidal silicon dioxide, hypromellose, microcrystalline cellulose, corn starch, talc.

Form of release: tablets 10 mg and 40 mg, 10, 50, 100 tablets per package. It is also available as a solution for injections of 0.1% solution in ampoules of 1 ml and 5 ml. The packages contain 10 or 100ampoules. 0.25% solution of Anaprilin is available in ampoules of 1 ml. In one package of this drug — 10 ampoules.

Tablets are available in a blister, in a box (â„–5, â„–10) and in a container in a box (â„–50).

Taking Anaprilin reduces heart rate, reduces blood pressure, myocardial need for oxygen saturation, promotes uterine contraction and increases musculature tone bronchi, normalizes the work of the digestive tract. People suffering from coronary heart disease, Anapriline helps to cope with attacks of angina and relieve them, reduces the risk of myocardial infarction, increases performance. People who regularly take Anapriline carry physical exertion more easily. In addition, they gradually reduce the need for nitroglycerin.

The result of Anaprilin action is noticeable even after a single use. Typically, eating propanol contributes to reducing systolic and diastolic pressure, no matter what position the patient is in: standing or lying down. By the end of the second week of taking the drug, sustained hypotensive effect is achieved

Indications for use

Anapriline is prescribed for angina, arterial hypertension (increased blood pressure), renal hypertension, coronary heart disease, angina, heart rate disorders caused by rheumatic heart damage, including arrhythmias, paroxymal and sinus tachycardia, extrasystolia, shimmery tachyarrhythmia, as well as in thyrotoxicosis and cases of intoxication with thimble drugs. It is recommended to take Anaprilin in glaucoma, essential tremor and as a prevention of migraines.

Method of use and dose

The drug should be drunk before eating, 15-30 minutes before eating. The tablet must be filled with plenty of water. The dosage and duration of treatment is selected by the doctor, taking into account individual problems of each patient.

Even after carefully studying the instructions for the use of Anapriline, never self-medicate.

For the treatment of hypertension in adults, the daily dosage may be 160-320 mg. However, treatment should be started with an initial dose, which is usually 40 mg twice a day. If necessary, the dosage can be gradually increased, but it is necessary to monitor the patient’s condition and well-being.

Each disease corresponds to its own dosage. For example, with angina, migraine, essential tremor, arousal initial dosage is as follows: 40 mg 2-3 times a day. For the treatment of arrhythmia, thyrotoxicosis and tachycardia, it is recommended to drink Anapriline at a dosage of 10mg to 40 mg 3-4 times a day.

Anapoline treatment after suffering myocardial infarction begins on the 5-21 day. The initial dose is 40 mg 4 times a day for the first four days of intake, then the daily dose of the drug can be increased to 80 mg. But in this case it is necessary to take Anapriline twice a day.

In open-angle glaucoma, a 15 percent solution of Anaprilin is prescribed to reduce intraocular pressure.

To relieve angina attack and heart rate disorders, it is best to perform injections with Anapriline solution, which should be performed only with the supervision of a doctor.

Anapolin treatment is carried out long, over several months. The drug is stopped gradually with a smooth reduction of the dose.

Older persons dosage is prescribed individually according to their condition and age. Individually, Anaprlin treatment is prescribed for children over three years with cardiovascular disorders. In this case, to determine the dosage of the drug it is necessary to adhere to the scheme: 0.25-05 mg/kg body weight 3 times a day.

Side effects

Despite good tolerability of the drug, Anapriline can cause a number of side effects, even if it is used correctly, according to all recommendations of a doctor. Among them are nausea, diarrhea, vomiting, constipation, dizziness, weakness, lethargy, hypotonia, allergic reactions, bronchopulmonary spasm, rest, cough, visual impairment, reduction of lacrimal fluid and how manifestation of this is dryness and soreness of the eye, Raynaud syndrome. With prolonged admission in rare cases, impotence is noted.

Admission of Anapriline is not recommended for people whose profession requires increased attention.



cannot be used after fresh myocardial infarction, hay fever, predilection for spasms of bronchi, bronchial asthma, diabetes mellitus, blood pressure disorders, heart failure, bradycardia, characterized by slowing heart rate to 60 beats per minute.

In no case can you take Anapriline in a hangover, you can’t combine the drug with alcohol, as the combination of spirits and Anapriline is dangerous and can cause a sharp downgrade blood pressure.

The instruction to the drug does not specify the effect of the drug on the condition of the pregnant woman, so the use of Anaprilin during pregnancy and during lactation is possible under the supervision of the doctor.

Smoking when treated with Anapolin can trigger the appearance of side effects such as rest, cough, bronchopulmonary spasm. In this case, it is possible to try treatment with other Anaprilin analogues: Inderal, Obzidane, Propranolol.

It is not recommended to combine Anapriline and Paroxin.

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