Description and pharmacological effect of
“Analgin” is an analgesic with analgesic, anti-inflammatory and antipyretic actions. “Analgin” is a derivative of pyrazolone. It is produced in several forms: tablets, injection solution and rectal suppositories. The main active substance of “Analgin” is sodium methamisole. One tablet of the drug contains 500 mg. Also the composition includes excipients: potato starch, talc, calcium stearate, sugar rafinade. The tablets are usually white or yellowish in color, taste bitter. Available in bundles of 10 pieces, in blisters (contour packages) of 10 pieces. The injection solution contains 250 mg (25 percent) or 500 mg (50 percent) of sodium methamisole. Rectal suppositories depending on dosage contain 100 mg or 250 mg of active substance. Powder “Analgina” quickly dissolves in water, which is very convenient if necessary in the shortest possible time to reach the maximum content of the drug in the body.
The components of analgin are quickly absorbed into the body and exert their effects within 20 to 40 minutes. Within two hours, the drug’s action reaches a maximum of.
Indications for use
prescribed “Analgin” for minor or moderately expressed pain syndrome, in particular, headache, myalgia, neuralgia, $ postoperative pain, dysmenoria, painful menstruation, renal or hepatic colic in complex therapy with spasmolytics. It is recommended to take the drug for fever caused by infectious and inflammatory diseases. “Analgin” can also be used to reduce heat, but it is necessary to establish a diagnosis and cause of the increase in body temperature.
Contraindications and side effects
It is not recommended to take “Analgin” with hypersensitivity to components of the drug and derivatives of pyrazolone (tributone, butadione), in case of propensity to bronchospasms, disorders of the kidney and liver, diseases of the blood. The drug should not be used during pregnancy, especially in the first trimester and for six weeks before delivery.
You cannot inject “Analgin” under the skin: irritation may occur.
Despite the good tolerability of “Analgin”, when taking the drug it is possible to show side effects, such as skin rash, swelling of Quinke, in rare cases — anaphylactic shock. When prone to bronchospasms, taking “Analgin” can trigger a bronchopulmonary attack. With long-term use of the drug leukopenia, agranulocytosis are possible. Also sometimes note impairment of the kidneys.
When overdosed, nausea, vomiting, diarrhea, abdominal pain, tinnitus, cramps, diathesis, rash on the skin can be observed. When these symptoms appear, gastric rinsing is necessary. Symptomatic therapy may be required in complex cases.
The method of use and dose of
“Analgin” is prescribed inside (tablets), intravenously or suggestively. The pills are best drunk after a meal. The dose for adults, according to the instructions for use, is 0.25-0.5 g 2 or 3 times a day, children – 5 -10 mg per 1 kg of body weight 3-4 times a day. With rheumatism, it is recommended to take 0.5-1 g three times a day.
The maximum daily dose of “Analgin” should not exceed 3 g.
In severe pain, “Analgin” is administered intramuscular or intravenously. Adults are prescribed 1-2 ml of solution for injection (25% or 50%) 2-3 times a day, but at the same time the daily dose should not exceed 2 g of the drug. Children are assigned 0.1-0.2 ml (50 percent) or 0.2-0.4 ml (25 percent) of “Analgin” solution for every 10 kg of body weight.